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No emphysema or damage was noted under observation with HDD. In vitro, the image quality of air-insufflated HDD was significantly improved as compared with that of saline-irrigated CD. Conclusion: Pressure-controlled 5—15 kPa air. The safety of tipepidine in children and adults has already been established.

It is reported that tipepidine inhibits G-protein-coupled inwardly rectifying potassium GIRK-channel currents. The inhibition of GIRK channels by tipepidine is expected to modulate the level of monoamines in the brain. The purpose of this open-label trial was to confirm whether treatment with tipepidine can improve symptoms in pediatric patients with ADHD. Subjects and methods: This was a 4-week, open-label, proof-of-efficacy pilot study for pediatric subjects with ADHD. Results: A comparison of baseline scores and 4-week end-point scores showed that all the ADHD-RS scores total scores, hyperimpulsive subscores, and inattentive subscores.

Physical inactivity is associated with decreased growth differentiation factor 11 in chronic obstructive pulmonary disease.

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The aim of this study is to investigate the association between the plasma GDF11 levels and various clinical parameters in patients with COPD. Patients and methods: Eighteen ex-smokers as control subjects and 70 COPD patients participated in the current study. We measured the levels of plasma GDF11 using immunoblotting, lung function, physical activity using a triaxial accelerometer, quadriceps strength, exercise capacity, and systemic inflammatory markers. We investigated the association between the levels of plasma GDF11 and these clinical parameters.

Furthermore, the levels of plasma GDF11 were significantly correlated with the physical activity, quadriceps strength, and exercise capacity. Moreover, the levels of plasma GDF11 were significantly correlated with the data of inflammatory markers.

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Although various factors were. Nuclear reactor fuel replacement system. Object: To permit the direction in which a fuel replacement unit is moving to be monitored by the operator. Structure: When a fuel replacement unit approaches an intermediate goal position preset in the path of movement, renewal of data display on a goal position indicator is made every time the goal position is changed. With this renewal, the prevailing direction of movement of the fuel replacement unit can be monitored by the operator.

When the control of movement is initiated, the co-ordinates of the intermediate goal point A are displayed on a goal position indicator. When the replacement unit reaches point A, the co-ordinates of the next intermediate point B are displayed, and upon reaching point B the co-ordinates of the last goal point C are displayed. Creating understanding of reproductive health. Yoko Komiyama, senior commentator of the Japan Broadcasting Corporation; Miyuki Nakamura , senior staff writer of Nihon Keizai Shimbun's Lifestyle News Department; and Miki Morimoto, staff writer for the Center for Research and Analysis on Global Issues Project 21, Asahi Shimbun, were introduced to population and reproductive health issues and the situation of women in Nepal during a December interregional study tour.

Upon returning to Japan, these representatives of three of Japan's major mass media groups shared their experiences with the general public through reports in newspapers, and on radio and television. Three-body problem in quantum mechanics: Hyperspherical elliptic coordinates and harmonic basis sets. Elliptic coordinates within the hyperspherical formalism for three-body problems were proposed some time ago [V. Aquilanti, S. Cavalli, and G. Grossi, J. Tolstikhin and H. Nakamura , J. Here we consider their role in providing a smooth transition between the known 'symmetric' and 'asymmetric' parametrizations, and focus on the corresponding hyperspherical harmonics.

These harmonics, which will be called hyperspherical elliptic, involve products of two associated Lame polynomials. We will provide an expansion of these new sets in a finite series of standard hyperspherical harmonics, producing a powerful tool for future applications in the field of scattering and bound-state quantum-mechanical three-body problems. Recently, secure quantum key distribution based on Deutsch's algorithm using the Bell state is reported Nagata and Nakamura , Int.

Our aim is of extending the result to a multipartite system. In this paper, we propose a highly speedy key distribution protocol. We present sequre quantum key distribution based on a special Deutsch-Jozsa algorithm using Greenberger-Horne-Zeilinger states.

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Bob has promised to use a function f which is of one of two kinds; either the value of f x is constant for all values of x, or else the value of f x is balanced, that is, equal to 1 for exactly half of the possible x, and 0 for the other half. Here, we introduce an additional condition to the function when it is balanced. Our quantum key distribution overcomes a classical counterpart by a factor O 2 N.

Cleaning device for steam units in a nuclear power plant. Purpose: To prevent radioactive contamination upon dismantling and inspection of steam units such as a turbine to a building containing such units and the peripheral area. Constitution: A steam generator indirectly heated by steam supplied from steam generating source in a separate system containing no radioactivity is provided to produce cleaning steam. A cleaning steam pipe is connected by way of a stop valve between separation valve of a nuclear power plant steam pipe and a high pressure turbine.

Upon cleaning, the separation valve is closed, and steam supplied from the cleaning steam pipe is flown into a condenser. The water thus condensated is returned by way of a feed water heater and a condenser to a water storage tank. The radiation protection design of CSR. Nakamura et. The equivalent dose at the shield surface and in the surrounding environment, skyshine neutron dose equivalent and air-induced radioactivity were also estimated in this study.

It is found that the most important environmental radiation impact component of CSR is the skyshine neutrons, and the environmental impact due to air and cooling water induced radioactivity were lesser.

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Nivolumab in the treatment of malignant melanoma: review of the literature. Intravenous administration of nivolumab was approved for the treatment of unresectable malignant melanoma in in Japan.

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When advanced melanoma patients were treated with nivolumab, median overall survival became longer. Overall survival rate was significantly better in nivolumab-treated melanoma patients than dacarbazine-treated melanoma patients. Therefore, nivolumab can become an alternative therapy for advanced malignant melanoma. Successful treatment of two cases of urorectal septum malformation sequence with oligohydramnios and severe respiratory failure.

We report herein the successful treatment of severe respiratory failure in two patients with urorectal septum malformation sequence and prenatally diagnosed oligohydramnios.

The patients showed significant hypoxic deterioration and persistent pulmonary artery hypertension soon after birth. The patients were successfully weaned from ECMO and artificial ventilation and discharged to home. Although termination of the pregnancy has often been selected for fetuses with oligohydramnios-related urorectal septum malformation sequence, our results suggest the opportunity for these fetuses to be treated using respiratory supports including HFO, NO, and ECMO after birth. Keywords: urorectal septum malformation sequence, oligohydramnios, pulmonary hypoplasia.

A Dancing Black Hole.

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Recently, stationary black holes have been successfully simulated for up to times of approximately M, where M is the mass of the black hole. Considering that the expected burst of gravitational radiation from a binary black hole merger would last approximately M, black hole codes are approaching the point where simulations of mergers may be feasible.

We will present two types of simulations of single black holes obtained with a code based on the Baumgarte-Shapiro-Shibata- Nakamura formulation of the Einstein evolution equations. One type of simulations addresses the stability properties of stationary black hole evolutions. The second type of simulations demonstrates the ability of our code to move a black hole through the computational domain.

This is accomplished by shifting the stationary black hole solution to a coordinate system in which the location of the black hole is time dependent. Rotary plug. Purpose: In a rotating plug of a reactor using a liquid metal as a coolant as in the case of a fbr type reactor, to prevent the ingress of Na vapor into the sliding surface of the rotating plug. Constitution: A rotating plug comprising a large disc covering the upper part of a reactor pressure vessel containing therein a liquid metal and forming surfaces for mounting a shielding device and various other devices, and at least one or more of small discs provided rotatably and eccentrically within said large disc, which is characterized in that an elastic member consisting of bellows and a sealing is interposed between said large disc and said small discs.

Combination therapy of vitamin D and vitamin K enabled a marked gradual increase in bone mineral density.

Keywords: fracture, vitamin D, vitamin K, bone mineral density. Device for preventing cooling water from flowing out of reactor. Object: To provide emergency cooling system, which can prevent cooling water bearing radioactivity from flowing to the outside of the reactor at the time of breakage of feedwater pipe, thus eliminating the possibility of exposure of the fuel rod to provide high reliability and also reducing the possibility of causing radioactive pollution.